LT4R1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11506-50, ES11506-100

Citations, Manuals and MSDS Available upon request.

Background: function:Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response., PTM:Phosphorylated by GRK6 upon leukotriene B4 binding; which promotes desensitization., similarity:Belongs to the G-protein coupled receptor 1 family., tissue specificity:Expressed at highest levels in heart, skeletal muscle and at lower levels in brain and liver. High level of expression in lymphoid tissues.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 38kD

Human Gene ID: 1241

Human SWISS Prot NO: Q15722

Subcellular Location: Cell membrane; Multi-pass membrane protein.

Research Use Only